Since the discovery of DNA, scientists have sought a simple, reliable, affordable way to change the genetic code. Jennifer Doudna, together with Emmanuelle Charpentier and Virginijus iknys, won the 2018 Kavli Prize in Nanoscience for their invention of the gene editing tool CRISPR-Cas9. This technique arose from research into how bacteria track down and destroy intruder DNA when infected by a virus. Now, scientists can reprogram the tool to disable or change almost any gene in order to research its function, heal an error, or add a helpful new trait.
To learn more about brilliant work of Kavli Prize Laureates, visit The Kavli Prize. To explore more of the biggest questions in science, click here.
This article is part of a special report, “The Biggest Questions in Science,” sponsored by The Kavli Prize. It was produced independently by Scientific American and Nature editors, who have sole responsibility for all the editorial content.
Subscribe to Support Independent Journalism
Great science journalism requires human expertise, time, effort and creativity. And it costs money. That’s why I and the journalists here at Scientific American hope you’ll join our community.
When you subscribe, you are supporting staff and freelance journalists who are passionate about telling science stories that are true, important and compelling. Our editors and reporters are often experts in their fields, which means they understand the nuances of big discoveries and can untangle the breakthroughs from the hype. With a subscription, you are also supporting rigorous fact-checking to ensure the words we publish are precise and accurate. And you’re supporting original illustrations, graphics and photos that bring you closer to an advanced laboratory, an ice sheet in Antarctica or a space mission in orbit. You’re helping us craft other types of high-quality journalism as well: Our newsletters are carefully written, edited and curated by staffers you have or will come to know and love. Our Science Quickly podcast is based on original reporting, collaboration with editors and scientists and exacting production.
Subscriptions keep this engine running so we can continue to deliver thoughtful, rigorous and independent science journalism to you. In an era of viral misinformation, this work is crucial. If you value what we do, I hope you’ll consider joining us as a subscriber