Cell Number Is Future Fat Fight Front

Your fat cell number stays constant, but the individual fat cells die and are replaced. Stopping that process could be a new front in the fat fight. Karen Hopkin reports.

Illustration of a Bohr atom model spinning around the words Science Quickly with various science and medicine related icons around the text

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


Podcast Transcript: Losing weight is no walk in the park. (Although a walk in the park wouldn’t hurt). Seems no matter what diet you try, those stubborn love handles just won’t go away. Part of the problem is that the bulk of your bulk is stored inside fat cells. And the number of fat cells you have is set before you reach adulthood. So if you chunked up as a child, that battalion of fat cells is with you for life. It’s enough to make you want to bury your face in a tray of brownies, I know.  But hold off. Because researchers from Stockholm think they’ve found a loophole.
 
The Swedish scientists confirmed that even after massive weight loss, the number of fat cells an adult has remains the same. But they discovered that individual fat cells don’t last a lifetime. Each year, about 10 percent of them die off. Of course new fat cells take their place, findings that appear in the online issue of the journal Nature. While that might not seem like a major victory, if scientists can figure out how to stop the replacement fat cells from being born, that would tip the scales in your favor. So you might just be able to have your cake and eat it too, and still fit into your pants.

—Karen Hopkin

60-Second Science is a daily podcast. Subscribe to this Podcast: RSS | iTunes

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe