New Issue: Science’s Impossible Questions. Read Now

1918 Flu Antibodies Alive and Well

Extremely elderly survivors of the 1918 flu pandemic still have active antibodies that recognize that virus. Karen Hopkin reports

Illustration of a Bohr atom model spinning around the words Science Quickly with various science and medicine related icons around the text

Join Our Community of Science Lovers!

[The following is an exact transcript of this podcast.

Some people never forget a face. Others never forget a flu. Even if they were infected more than 90 years ago. A team of American scientists studied 32 people who survived the 1918 flu epidemic. That virus, also called the Spanish flu, killed an estimated 20 to 100 million people worldwide.

Of course many more survived, and some are still around today. The scientists tracked them down and took a small sample of their blood. And they found that all 32 people they tested still had circulating antibodies that could recognize the 1918 flu strain. What’s even more remarkable is that these immune molecules still work. Injecting the antibodies into mice protected the animals from experimental infection with the virus. The results were published online in the journal Nature on August 13th.


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


The scientists say that these elder antibodies could guide the way to new therapies to ward off flu should a virus similar to the 1918 strain arise. In the meantime, I guess you can be thankful that as your joints grow creaky and your vision fades, at least your immune system stays on its feet.

—Karen Hopkin

60-Second Science is a daily podcast. Subscribe to this Podcast: RSS | iTunes 

Subscribe to Support Independent Journalism

Great science journalism requires human expertise, time, effort and creativity. And it costs money. That’s why I and the journalists here at Scientific American hope you’ll join our community.

When you subscribe, you are supporting staff and freelance journalists who are passionate about telling science stories that are true, important and compelling. Our editors and reporters are often experts in their fields, which means they understand the nuances of big discoveries and can untangle the breakthroughs from the hype. With a subscription, you are also supporting rigorous fact-checking to ensure the words we publish are precise and accurate. And you’re supporting original illustrations, graphics and photos that bring you closer to an advanced laboratory, an ice sheet in Antarctica or a space mission in orbit. You’re helping us craft other types of high-quality journalism as well: Our newsletters are carefully written, edited and curated by staffers you have or will come to know and love. Our Science Quickly podcast is based on original reporting, collaboration with editors and scientists and exacting production.

Subscriptions keep this engine running so we can continue to deliver thoughtful, rigorous and independent science journalism to you. In an era of viral misinformation, this work is crucial. If you value what we do, I hope you’ll consider joining us as a subscriber

Thank you,

Jeanna Bryner, Editor in Chief, Scientific American

Subscribe