1918 Flu Antibodies Alive and Well

Extremely elderly survivors of the 1918 flu pandemic still have active antibodies that recognize that virus. Karen Hopkin reports

Illustration of a Bohr atom model spinning around the words Science Quickly with various science and medicine related icons around the text

Join Our Community of Science Lovers!

[The following is an exact transcript of this podcast.

Some people never forget a face. Others never forget a flu. Even if they were infected more than 90 years ago. A team of American scientists studied 32 people who survived the 1918 flu epidemic. That virus, also called the Spanish flu, killed an estimated 20 to 100 million people worldwide.

Of course many more survived, and some are still around today. The scientists tracked them down and took a small sample of their blood. And they found that all 32 people they tested still had circulating antibodies that could recognize the 1918 flu strain. What’s even more remarkable is that these immune molecules still work. Injecting the antibodies into mice protected the animals from experimental infection with the virus. The results were published online in the journal Nature on August 13th.


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


The scientists say that these elder antibodies could guide the way to new therapies to ward off flu should a virus similar to the 1918 strain arise. In the meantime, I guess you can be thankful that as your joints grow creaky and your vision fades, at least your immune system stays on its feet.

—Karen Hopkin

60-Second Science is a daily podcast. Subscribe to this Podcast: RSS | iTunes 

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe