Feisty Male Fruit Flies Calmed By Females

Exposure to female fruit fly pheromones activate neurons in male brains that made the males less aggressive with each other. Christopher Intagliata reports.

Illustration of a Bohr atom model spinning around the words Science Quickly with various science and medicine related icons around the text

Join Our Community of Science Lovers!

Fruit flies may seem pretty innocuous, to us. But in their own little world, male fruit flies are aggressive fighters, who will headbutt and shove each other…even box. There is one thing that'll calm them down though: the female touch.

Researchers raised males with varying amounts of contact with the fruit fly fairer sex. And they found that males who'd spent an entire day hanging out with ladies—including a chance to copulate—were more peaceable than those who had lacked such contact.

The researchers thought the sex act might be the secret. But the sex alone won't do the trick. The key to peace was prolonged physical contact with females—which causes female pheromones to rub off on the males. Those chemical compounds activate about 20 neurons in the male brain, which tamp down the brain's aggression circuit, and bingo: no more fighting. The results appear in the journal Nature Neuroscience. [Quan Yuan et al., Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila]


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


As for human aggression, this study doesn't say much. But we do share genes with flies, and our neural circuitry has similarities. So the researchers say work on hot-headed flies could someday clue us in to why humans fly into a rage.

—Christopher Intagliata

[The above text is a transcript of this podcast.]

[Scientific American is part of Nature Publishing Group.]

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe