Post-Patriot Act Pathogen Research: Less Bang per Buck

New guidelines governing research on potential bioweapons after 9/11 have cut down the number of research papers published per funding dollar. Cynthia Graber reports

Illustration of a Bohr atom model spinning around the words Science Quickly with various science and medicine related icons around the text

Join Our Community of Science Lovers!

The Patriot Act and the Bioterrorism Preparedness Act were passed in 2001 and 2002. These laws in part cover research on pathogens and toxins thought to have potential as bioweapons.

The Bush administration increased funding for research on such toxins and pathogens—but the laws added a great many procedural steps for such research, and restricted who could work with the microbes. Scientists at Carnegie Mellon recently evaluated the impact of the laws on research in the Proceedings of the National Academy of Sciences. [Elisabeth Casman et al., http://bit.ly/ddGnoX]

They checked out work with anthrax bacteria, the ebola virus, along with a control, Klebsiella bacteria. The researchers did find an increase in the total number of papers published. But before the laws, 17 anthrax papers appeared per million dollars of funding. With the restrictions, only three papers appeared per million dollars of funding. For ebola, the numbers dropped from 14 to six papers per million dollars. Figures for the control stayed the same.


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


The bottom line: the study authors say that research on anthrax and ebola has not been seriously inhibited. But it has been made significantly less efficient.

—Cynthia Graber

[The above text is an exact transcript of this podcast.]

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe