Where the Desire for Change Resides

Scientists have found an area of the brain that becomes highly active when we finally decide to explore the unknown. Christie Nicholson reports

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


[Below is the original script. But a few changes may have been made during the recording of this audio podcast.]

Most of us know two kinds of people: those who crave change and others who would rather stick to routine.

And people suffering from illnesses like Alzheimer’s or obsessive compulsive disorder often don’t have much of a choice. Typically they prefer a highly predictable environment.

But most of us, at some point, recall a moment where we decided to leap into the unknown and take a chance to change our lives, hopefully for the better.

Well Duke University scientists have discovered a part of the brain that sparks a desire to explore.

The researchers followed monkeys given a choice.  They could either stick with a known reward or explore other possible “mystery” rewards that they had learned could sometimes be better than the familiar prize .

By studying the level of firing of individual neurons in the brain’s posterior cingulate cortex, the scientists could predict whether the monkey would take the chance to explore new options. The neurons fired more vigorously when the monkey made up his mind to go for it.

Learning how this specific area of the brain functions may lead to new insight into how we adapt to novel environments. And could help those who feel trapped by the need for the same old routine.

—Christie Nicholson

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe