Bacteria Lowers Mosquito-Transmission of Malaria, Dengue

Mosquitoes that harbor a soil microbe called Chromobacterium Csp_P have a harder time catching dengue virus and the malarial parasite. Christopher Intagliata reports

Illustration of a Bohr atom model spinning around the words Science Quickly with various science and medicine related icons around the text

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


The human microbiome is the community of tiny organisms that live on us and inside us. These critters play vital roles in our health. They calibrate our immune systems, ward off pathogenic bacteria, even affect our weight. But if we stop the navel gazing—literally, because some scientists are actually measuring belly button bacteria—there's a whole lot to be found in the microbiomes of other organisms, too.

Take the pesky mosquito. A few years back, scientists found a soil microbe called Chromobacterium Csp_P living in the guts of mosquitoes in Panama. Upon further study, the researchers say this mosquito-occupant could be a remarkably versatile weapon to fight malaria and dengue fever. Because Chromobacterium shortens the lifespan of disease-transmitting mosquito species that harbor it; and kills their larvae outright. It also reduces mosquitoes' ability to catch the dengue virus, or the malarial parasite; and it kills both pathogens in the lab. Those findings are in the journal PLoS Pathogens. [Jose Luis Ramirez et al.: Chromobacterium Csp_P Reduces Malaria and Dengue Infection in Vector Mosquitoes and Has Entomopathogenic and In Vitro Anti-pathogen Activities]

The researchers say this Chromobacterium strain could someday guide the development of new drugs. Or serve as a more environmentally-friendly stand-in for pesticides. But they also say that, as with many disease-control strategies, there's no one silver bullet. Drugs, vaccines, and education will still be crucial to keeping mosquito-borne killers in check. Along with good old vector control: in this case, fighting bugs with bugs.

—Christopher Intagliata

[The above text is a transcript of this podcast.]
 

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe