New Issue: Orbital Catastrophe Ahead? Read Now

Blood Test Forecasts Concussion Severity

Levels of a protein fragment in the blood paralleled how long head injuries benched hockey players. Ingrid Wickelgren reports

Join Our Community of Science Lovers!


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


Confusion is one symptom of a concussion. But confusion may also characterize decisions about how soon to let an athlete play after taking a hit to the head. Sizing up symptoms such as dizziness and nausea is subjective, after all. Now a study suggests that a blood test could objectively determine whether or not the damage is bad enough to put a player on the bench. The work is in the Journal of Neurotrauma. [Robert Siman et al, Serum SNTF Increases in Concussed Professional Ice Hockey Players and Relates to the Severity of Post Concussion Symptoms]

A strong blow to the head causes chemical changes within nerve cells that damage their structural proteins. Among the debris is a protein fragment called SNTF—which in more severe cases, spills into the bloodstream.

The new study followed 20 professional hockey players who got concussions with symptoms that lasted six days or more. And blood levels of SNTF were much higher one hour to six days later than were levels of the protein fragment in eight other athletes who had gotten concussions that cleared up within five days. Levels were also low in 45 non-concussed players tested during the preseason.

A blood test for SNTF might thus forecast recovery time from a head injury. Combined with other neurological tests, levels of this molecule could help doctors tell athletes when it’s safe to suit up again.
 
—Ingrid Wickelgren
 
[The above text is a transcript of this podcast.]

Subscribe to Support Independent Journalism

Great science journalism requires human expertise, time, effort and creativity. And it costs money. That’s why I and the journalists here at Scientific American hope you’ll join our community.

When you subscribe, you are supporting staff and freelance journalists who are passionate about telling science stories that are true, important and compelling. Our editors and reporters are often experts in their fields, which means they understand the nuances of big discoveries and can untangle the breakthroughs from the hype. With a subscription, you are also supporting rigorous fact-checking to ensure the words we publish are precise and accurate. And you’re supporting original illustrations, graphics and photos that bring you closer to an advanced laboratory, an ice sheet in Antarctica or a space mission in orbit. You’re helping us craft other types of high-quality journalism as well: Our newsletters are carefully written, edited and curated by staffers you have or will come to know and love. Our Science Quickly podcast is based on original reporting, collaboration with editors and scientists and exacting production.

Subscriptions keep this engine running so we can continue to deliver thoughtful, rigorous and independent science journalism to you. In an era of viral misinformation, this work is crucial. If you value what we do, I hope you’ll consider joining us as a subscriber

Thank you,

Jeanna Bryner, Editor in Chief, Scientific American

Subscribe