Medicine
A Deluge of New Drugs for COVID
Two years into the pandemic, the COVID-19 drugs pipeline is primed to pump out novel treatments—and fresh uses for familiar therapies.
Stories by Heidi Ledford
Medicine
Can Drugs Reduce the Risk of Long COVID? What Scientists Know So Far
Researchers are trying to establish whether existing COVID-19 vaccines and treatments can prevent lasting symptoms
Public Health
How Severe Are Omicron Infections?
A rapidly spreading variant could dangerously strain health-care systems, even if the severe disease risk is relatively low for an individual
Public Health
Should Children Get COVID Vaccines? What the Science Says
With vaccination campaigns underway in some countries while others weigh the options, Nature looks at the evidence for vaccinating younger people
Public Health
Six Months of COVID Vaccines: What 1.7 Billion Doses Have Taught Scientists
At a pivotal moment in the pandemic, Nature explores key questions about the vaccines that countries are racing to deliver while viral variants spread around the globe
Medicine
Delaying a COVID Vaccine’s Second Dose Boosts Immune Response in the Elderly
People older than 80 who waited 11 to 12 weeks for their second jab had higher peak antibody levels than did those who waited only three weeks
Medicine
Malaria Vaccine Shows Promise—Now Come Tougher Trials
Preliminary results suggest the vaccine is up to 77 percent effective in young children, but researchers await larger studies
Medicine
How Could a COVID Vaccine Cause Blood Clots?
Researchers are searching for possible links between unusual clotting and the Oxford-AstraZeneca coronavirus vaccine
Biotech
Scientists Grew Tiny Tear Glands in a Dish—Then Made Them Cry
Organoids made of tear-producing cells offer chances to study, and possibly treat, eye disorders
Medicine
COVID Antibody Treatments Show Promise for Preventing Severe Disease
Uptake by patients and physicians has been low in the U.S. even though some therapies have been authorized for months
Medicine
Moderna COVID Vaccine Becomes Second to Get U.S. Authorization
Two RNA vaccines will be useful as U.S. infections surge, but the speedy authorizations complicate clinical trials
Medicine
Coronavirus Drug Remdesivir Shortens Recovery but Is Not a Magic Bullet
Despite conflicting data, the highly anticipated results will make the treatment a standard of care in the U.S.
Medicine
Evidence for Convalescent Plasma Coronavirus Treatment Lags behind Excitement
Despite calls for more rigorous clinical trials, the Food and Drug Administration has granted an emergency authorization for the therapy
Medicine
The Coronavirus Outbreak Could Make it Quicker and Easier to Trial Drugs
Remote clinical trials and other changes could permanently alter pharmaceutical development
Biotech
CRISPR Gene Editing in Human Embryos Wreaks Chromosome Mayhem
Three studies showing large DNA deletions and reshuffling heighten safety concerns about heritable genome editing
Medicine
Chloroquine Hype Is Derailing the Search for Coronavirus Treatments
With politicians touting the potential benefits of malaria drugs to fight COVID-19, some people are turning away from clinical trials of other therapies
Biotech
Quest to Use CRISPR against Disease Gains Ground
As the first clinical trial results trickle in, researchers look ahead to more sophisticated medical applications for genome editing
Biotech
CRISPR Treatment Inserted Directly into the Body for the First Time
The experiment tests a gene-editing therapy for a hereditary blindness disorder
Public Health
Why U.S. Officials Investigating Mysterious Vaping Deaths Are Focusing on Flavorings
As lung injuries among e-cigarette users mount amid a youth vaping epidemic, the impact of new restrictions remains unclear
Neurology
Cancer Cells Have “Unsettling” Ability to Hijack the Brain’s Nerves
The startling discovery could open up avenues for treating some aggressive tumors
