In 1904 a woman in Italy confronted two life-threatening events: first, diagnosis with cancer of the uterine cervix, then a dog bite. Doctors delivered the rabies vaccine for the bite, and subsequently her “enormously large” tumor disappeared (“il tumore non esisteva più”). The woman lived cancer-free until 1912. Soon thereafter several other Italian patients with cervical cancer also received the vaccine—a live rabies virus that had been weakened. As reported by Nicola De Pace in 1910, tumors in some patients shrank, presumably because the virus somehow killed the cancer. All eventually relapsed and died, however.