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Coffee Reduces Risk of Bladder Cancer

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Researchers have long considered smoking a risk factor for bladder cancer, a disease that strikes about 55,000 Americans each year. But the results of a new study published in the January 2001 issue of the Journal of Epidemiology and Community Health suggest that risk may be far higher than previously thought. The same study, however, indicates that coffee may protect against bladder cancer, especially among smokers. Analyzing data from 500 diagnosed cases of bladder cancer, as well as 1,000 control subjects, the researchers found that non-coffee drinking smokers were seven times more likely to develop the disease as non-smokers. Coffee-drinking smokers, on the other hand, were only three times more at risk. Coffee thus appears to somehow dilute the harmful effect of tobacco use on the bladder. Previous studies have suggested that caffeine might discourage mutations from forming, perhaps by inducing activity in an enzyme known as CYP1A2. But only further research will reveal exactly how coffee consumption protects against this disease.

Kate Wong is an award-winning science writer and was formerly senior editor for features at Scientific American, where she focused on evolution, ecology, anthropology, archaeology, paleontology and animal behavior. She is fascinated by human origins, which she has covered for nearly 30 years. Recently she has become obsessed with birds. Her reporting has taken her to caves in France and Croatia that Neandertals once called home to the shores of Kenya’s Lake Turkana in search of the oldest stone tools in the world, as well as to Madagascar on an expedition to unearth ancient mammals and dinosaurs, the icy waters of Antarctica, where humpback whales feast on krill, and a “Big Day” race around the state of Connecticut to find as many bird species as possible in 24 hours. Wong is co-author, with Donald Johanson, of Lucy’s Legacy: The Quest for Human Origins. She holds a bachelor of science degree in biological anthropology and zoology from the University of Michigan. Follow her on Bluesky @katewong.bsky.social

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