Are There Links between Pesticides and Other Chemicals to Thyroid Disease?

Although the causes of thyroid disease are unknown, genetics are a major factor. Researchers, however, also report exposure to some chemicals, especially among women, may be linked to thyroid problems

Join Our Community of Science Lovers!

Dear EarthTalk: Instances of people with thyroid problems seems to be on the rise. Is there an environmental connection?—Dora Light, Waukesha, Wis.

The American Cancer Society reports that thyroid cancer is one of the few cancers that have been on the rise in recent decades, with cases increasing six percent annually since 1997. Many researchers, however, attribute these increases to our having simply gotten better at detection. Regardless, exposures to stress, radiation and pollutants have been known to increase a person’s risk of developing thyroid problems.

Thyroid disease takes two primary forms. Hyperthyroidism occurs when the thyroid produces too much of the T3 and T4 hormones that regulate metabolism. This can cause a racing heart, weight loss, insomnia and other problems. In cases of hypothyroidism, the body produces too few hormones, so we feel fatigued and may gain weight, among other symptoms. According to the American Thyroid Association (ATA), many people with thyroid problems don’t realize it, as symptoms can be mistaken for other problems or attributed to lack of sleep. Thyroid problems in children can delay or impair neurological development.

Doctors are not sure why some people are prone to thyroid disease while others aren’t, but genetics has much to do with it. One recent UCLA study found that genetic background accounts for about 70 percent of the risk. However, researchers have begun to find links between increased risk of thyroid disease and exposure to certain chemicals, especially among women. “Pesticide Use and Thyroid Disease among Women in the Agricultural Health Study,” published in the American Journal of Epidemiology in 2002, found that Iowa and North Carolina women married to men using such pesticides as aldrin, DDT and lindane were at much higher risk of developing thyroid disease than women in non-agricultural areas. According to Dr. Whitney S. Goldner, lead researcher on the study, 12.5 percent of the 16,500 wives evaluated developed thyroid disease compared to between 1 and 8 percent in the general population.


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


It’s not just farm women who should worry. Trace amounts of chemical pesticides and fertilizers most certainly end up in some of the food we eat. The nonprofit group Beyond Pesticides warns that some 60 percent of pesticides used today have been shown to affect the thyroid gland’s production of T3 and T4 hormones. Commercially available insecticides and fungicides have also been implicated.

Likewise, some chemicals used in plastics and flame retardants contain toxins shown to trigger thyroid problems in those genetically predisposed. And a 2007 study at the University of Texas Health Sciences Center at San Antonio found that triclosan, an anti-bacterial agent found in everything from hand soaps to facial tissues to toys—it’s present in the bloodstreams of three out of every four Americans—could be causing some mothers’ thyroid glands to send signals to fetuses that may in turn contribute to autism.

An increasing number of doctors now believe that hypothyroidism could be precipitated by a dietary deficiency in iodine, a trace element found in the thyroid’s T3 and T4 hormones and essential in small amounts for good health. Besides eating more seafood, switching to iodized salt and/or taking iodine supplements can boost iodine intake without the need for medications. But too much iodine is not healthy, so always consult with your doctor before embarking on any new health or diet regimen.

CONTACTS: ATA, www.thyroid.org; Beyond Pesticides, www.beyondpesticides.org.

EarthTalk® is written and edited by Roddy Scheer and Doug Moss and is a registered trademark of E – The Environmental Magazine (www.emagazine.com). Send questions to:earthtalk@emagazine.com. Subscribe: www.emagazine.com/subscribe; Request a Free Trial Issue: www.emagazine.com/trial.

It’s Time to Stand Up for Science

If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.

I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.

If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.

In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.

There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.

Thank you,

David M. Ewalt, Editor in Chief, Scientific American

Subscribe