When James Allison started researching T cells in the 1980s, he didn’t intend to cure cancer. He was just interested in the immune system. More than thirty years later, his work forms the basis for many of the most promising cancer therapeutics available today. Allison is now the chief immunologist at the University of Texas MD Anderson Cancer Center and the winner of the 2018 Dr. Paul Janssen Award but he still remembers his roots in research. And he’s reaching back to them to drive his immunology revolution forward once again.