Chemistry Nobelist Attacks Macular Degeneration
A team led by chemistry Nobel laureate Walter Kohn has developed a tool for the diagnosis of the specific visual distortions perceived by any individual suffering from macular degeneration. Mariette DiChristina reports

SUBSCRIBE TO Science Quickly
Macular degeneration causes visual distortion and even complete loss of sight. When the wife of chemistry Nobel laureate Walter Kohn was diagnosed with macular degeneration, he wanted to do something. I spoke with him at the recent Lindau Nobel Laureate meeting in Germany.
“We are developing a corrective device, including interaction with the patient, who is following a certain routine and who tells us his perceptions that arise.”
A macular degeneration patient looks at a completely regular grid on a computer screen. But because of the condition, the grid will appear distorted. The patient uses a mouse to adjust the grid to appear normal.
On supporting science journalism
If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.
“We will receive from the patient an edited piece of graph paper. And from the way the patient edits it, we can tell what the distortions are that he perceives and from these we can then develop devices that correct his distortions.”
—Mariette DiChristina
[The above text is a transcript of this podcast.]
It’s Time to Stand Up for Science
If you enjoyed this article, I’d like to ask for your support. Scientific American has served as an advocate for science and industry for 180 years, and right now may be the most critical moment in that two-century history.
I’ve been a Scientific American subscriber since I was 12 years old, and it helped shape the way I look at the world. SciAm always educates and delights me, and inspires a sense of awe for our vast, beautiful universe. I hope it does that for you, too.
If you subscribe to Scientific American, you help ensure that our coverage is centered on meaningful research and discovery; that we have the resources to report on the decisions that threaten labs across the U.S.; and that we support both budding and working scientists at a time when the value of science itself too often goes unrecognized.
In return, you get essential news, captivating podcasts, brilliant infographics, can't-miss newsletters, must-watch videos, challenging games, and the science world's best writing and reporting. You can even gift someone a subscription.
There has never been a more important time for us to stand up and show why science matters. I hope you’ll support us in that mission.