New Issue: Orbital Catastrophe Ahead? Read Now

U.S. Launches Apollo-Style Mission to Harness AI and Big Data for Scientific Discovery

A new federal initiative aims to accelerate scientific discovery by uniting artificial intelligence with large federal datasets

A human finger pushes a touch-screen button and activates futuristic artificial intelligence

gorodenkoff/Getty Images

Join Our Community of Science Lovers!

On Monday President Donald Trump signed an executive order aimed at accelerating science using artificial intelligence, an effort dubbed the “Genesis Mission.”

The order frames the race for global technological dominance in AI as “comparable in urgency and ambition to the Manhattan Project,” referring to the development of the atomic bomb during World War II. The order comes at a moment when federal agencies have seen massive cuts to research grants and funding—and Trump’s order does not set out a defined budget for Genesis.

National security, scientific discovery and energy innovation are all highlighted as top priorities in the order, which states that federal scientific datasets such as those managed by NASA, the National Institutes of Health and other government science agencies will be critical to this work. Together, these add up to many billions of measurements, images and computer simulations about everything from the deep ocean to outer space to the human genome.


On supporting science journalism

If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.


In a press call on Monday, science adviser to the president Michael Kratsios called the Genesis Mission “the largest marshaling of federal scientific resources since the Apollo program,” CBS News reported.

“The Genesis mission will use AI to automate experiment design, accelerate simulation and generate protective models for everything from protein folding to fusion plasma dynamics. This will shorten discovery timelines from years to days or even hours, empowering scientists to test bolder hypotheses and discover breakthroughs currently unreachable,” Kratsios said.

Trump’s order gives the Department of Energy 60 days to identify 20 high-priority challenges to tackle. It has 90 days to catalog all the computing resources at its disposal, 120 days to set out a plan for harnessing data from both federal sources and other research institutes and 270 days to show that its plan can make progress on at least one of the identified challenges.

Top priorities for these challenges include breakthroughs in fusion energy, advanced nuclear reactors, electric-grid modernization, new materials, quantum computing and lifesaving medicines, according to a DOE webpage. A central goal of the mission is “to double the productivity and impact of American research and innovation within a decade” by augmenting and not replacing human scientists.

Given the vast sums of money that are already pouring into AI, it remains unclear how much this effort will cost. The DOE lists Nvidia, Anthropic, OpenAI, Advanced Micro Devices, Amazon Web Services, Microsoft, IBM and Google as collaborators in the effort, although what their exact contribution will be is also unknown.

Deni Ellis Béchard was formerly Scientific American’s senior writer for technology. He is author of 10 books and has received a Commonwealth Writers’ Prize, a Midwest Book Award and a Nautilus Book Award for investigative journalism. He holds two master’s degrees in literature, as well as a master’s degree in biology from Harvard University. His most recent novel, We Are Dreams in the Eternal Machine, explores the ways that artificial intelligence could transform humanity. You can follow him on X, Instagram and Bluesky @denibechard

More by Deni Ellis Béchard

Subscribe to Support Independent Journalism

Great science journalism requires human expertise, time, effort and creativity. And it costs money. That’s why I and the journalists here at Scientific American hope you’ll join our community.

When you subscribe, you are supporting staff and freelance journalists who are passionate about telling science stories that are true, important and compelling. Our editors and reporters are often experts in their fields, which means they understand the nuances of big discoveries and can untangle the breakthroughs from the hype. With a subscription, you are also supporting rigorous fact-checking to ensure the words we publish are precise and accurate. And you’re supporting original illustrations, graphics and photos that bring you closer to an advanced laboratory, an ice sheet in Antarctica or a space mission in orbit. You’re helping us craft other types of high-quality journalism as well: Our newsletters are carefully written, edited and curated by staffers you have or will come to know and love. Our Science Quickly podcast is based on original reporting, collaboration with editors and scientists and exacting production.

Subscriptions keep this engine running so we can continue to deliver thoughtful, rigorous and independent science journalism to you. In an era of viral misinformation, this work is crucial. If you value what we do, I hope you’ll consider joining us as a subscriber

Thank you,

Jeanna Bryner, Editor in Chief, Scientific American

Subscribe