Autophagy, Illustrated

A graphic from the Scientific American archive shows how cells clean house—the basics behind this year’s Nobel Prize in Physiology or Medicine

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Earlier this week, Yoshinori Ohsumi was awarded the 2016 Nobel Prize in Physiology or Medicine for his work on the underlying mechanisms of autophagy—the process by which cells break down and recycle their own contents. How does autophagy work? Here are the basics, as drawn for the article “How Cells Clean House,” by Vojo Deretic and Daniel Klionsky (Scientific American, May 2008).

Credit: JEN CHRISTIANSEN

For more on autophagy, listen to Juleen Zierath, chair of the Nobel Committee for Physiology or Medicine, explain Ohsumi's research on Science Talk.

Jen Christiansen is an information designer, visual science communicator and author of the book Building Science Graphics: An Illustrated Guide to Communicating Science through Diagrams and Visualizations. She began her publishing career in New York City at Scientific American, moved to Washington, D.C., to join the art department of National Geographic, spent four years as a freelance science communicator and then returned to Scientific American for a second stint, during which she became the magazine’s first graphics-specific art director. In that role, she established a consistent data visualization and diagram philosophy across all articles. She writes and presents on topics ranging from reconciling her love for art and science to her quest to learn more about the pulsar chart on Joy Division’s Unknown Pleasures album cover. Her work can be viewed at www.jenchristiansen.com

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